Purpose
Most sequence tools show which bases are present, but not always how structural complexity changes across a region in a way that is fast to inspect and compare.
research tools · 2026
EntropySeq
Sequence-analysis tool that uses Shannon entropy to inspect DNA complexity and compositional variation across genomic regions.
My role
Designer and engineer
Status
active
Methods
- Python
- Streamlit
- Sequence parsing
- Sliding windows
- Shannon entropy
- Plotting / visualization
- Genomic region comparison
Outputs
- Interactive sequence profile
- Low-entropy window table
- FASTA and CSV exports
Result
A runnable browser and CLI workflow for comparing local sequence complexity with explicit parameters.
Implementation
How it works
EntropySeq calculates Shannon entropy across sliding windows and reports local complexity changes, repetitive regions, and unusually uniform sequence segments.
EntropySeq is built as a Streamlit application and CLI. The browser route supports pasted or uploaded sequences, sliding-window profiles, low-entropy window extraction, and FASTA export while keeping interpretation explicitly non-diagnostic.